1,3-ASYMMETRIC INDUCTION IN THE ALDOL REACTIONS OF ALPHA-METHYLENE-BETA-ALKOXY ALDEHYDES

Authors
PATERSON I BOWER S TILLYER RD
Citation
I. Paterson et al., 1,3-ASYMMETRIC INDUCTION IN THE ALDOL REACTIONS OF ALPHA-METHYLENE-BETA-ALKOXY ALDEHYDES, Tetrahedron letters, 34(27), 1993, pp. 4393-4396
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
27
Year of publication
1993
Pages
4393 - 4396
Database
ISI
SICI code
0040-4039(1993)34:27<4393:1IITAR>2.0.ZU;2-L
Abstract
The aldol reactions of the alpha-methylene-beta-alkoxy aldehydes 3 and 6 were examined for a range of Ti(IV), Sn(II), and B enolates. The se nse and level of 1,3-asymmetric induction (up to 95% ds) varies with t he enolate structure and the beta-hydroxyl protecting group in the ald ehyde.