BORANE COMPLEXES OF VINBLASTINE TYPE DIINDOLE DERIVATIVES

Citation
M. Balazs et al., BORANE COMPLEXES OF VINBLASTINE TYPE DIINDOLE DERIVATIVES, Tetrahedron letters, 34(27), 1993, pp. 4397-4398
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
34
Issue
27
Year of publication
1993
Pages
4397 - 4398
Database
ISI
SICI code
0040-4039(1993)34:27<4397:BCOVTD>2.0.ZU;2-#
Abstract
While investigating the ferric chloride mediated coupling1 of catharan thine (1) with vindoline (3) and their derivatives (2,4), the borane c omplexes of 15',20'-anhydrovinblastine2 (AVLB), 20'-deethyl-AVLB and N -demethyl-AVLB (9,10,11) have been synthesized. The corresponding base s (6,7 and 8) have also been obtained in high yield.