STUDY OF ISCHEMIC MYOCARDIAL BUFFERING CAPACITY IN PERFUSED RAT-HEARTTHROUGH RAPIDLY INTERLEAVED H-1 AND P-31 MRS MEASUREMENTS

Authors
SCHUSSHEIM AE RADDA GK
Citation
Ae. Schussheim et Gk. Radda, STUDY OF ISCHEMIC MYOCARDIAL BUFFERING CAPACITY IN PERFUSED RAT-HEARTTHROUGH RAPIDLY INTERLEAVED H-1 AND P-31 MRS MEASUREMENTS, Magnetic resonance in medicine, 30(1), 1993, pp. 115-119
Citations number
27
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
Magnetic resonance in medicine → ACNP
ISSN journal
07403194
Volume
30
Issue
1
Year of publication
1993
Pages
115 - 119
Database
ISI
SICI code
0740-3194(1993)30:1<115:SOIMBC>2.0.ZU;2-#
Abstract
We present a method for the direct correlation of quantitative changes in lactate concentration and intracellular pH during global ischemia in the perfused rat heart using rapidly interleaved P-31 MRS and water -suppressed H-1 MRS acquisitions. The ischemic myocardial buffering ca pacity was determined and found to be consistent with previous experim entation.