Local-regional recurrences of the pelvis occur as an isolated event in
4 to 24 per cent of rectal cancer patients. While radiation therapy m
ay provide temporary relief of pain due to recurrence, only a salvage
pelvic exenteration offers hope of cure in these patients. We identifi
ed and reviewed 16 rectal cancer cases with local-regional recurrence
who underwent salvage pelvic exenteration for cure. There were eight m
en and eight women. The primary cancer was treated by AP resection (3)
, low anterior resection (6), Hartman's resection (6), or local excisi
on (1). Tumor at primary resection was Stage I for two patients, II fo
r five patients, and nine patients were Stage III. Adjuvant radiation
had been given to nine patients. The type of exenteration required for
curative resection was anterior (3), posterior (6), total (4), or tot
al-sacral (3). One patient died postoperatively. Survival calculations
were from time of salvage exenteration until death or last follow-up.
Only six deaths have occurred with a 5-year survival of 49 per cent.
Mean survival for the total group was 31 months. Salvage pelvic exente
ration should be given high priority in managing local-regional recurr
ences of the pelvis and provides worth-while survival.