Objective: To present the first documented case of human T-lymphotropi
c virus type I (HTLV-1) associated myelopathy/tropical spastic parapar
esis in the Australian population. Clinical features: A 31-year-old Ab
original man with an 18-month history of progressive weakness of the l
egs was found to have an upper motor neurone weakness of all limbs ass
ociated with sphincteric disturbance and impotence. HTLV-I antibodies
were detected in his serum and no other cause for the patient's myelop
athy could be found. Intervention and outcome: He was counselled regar
ding HTLV-I associated myelopathy/tropical spastic paraparesis. Conclu
sion: This is the first description of HTLV-I associated myelopathy/tr
opical spastic paraparesis in an Australian. In cases of spinal cord d
isorder without evidence of compression we recommend serological testi
ng for HTLV-I, especially in Aboriginal patients. Additionally, testin
g of blood donors for this retrovirus needs consideration.