M. Largeron et al., INFLUENCE OF STERIC CROWDING ON THE ELECTROCHEMICAL REDUCTION OF SUBSTITUTED TERTIARY PYRIDYLCARBOXAMIDES IN AQUEOUS ACIDIC MEDIUM, Perkin transactions. 2, (3), 1997, pp. 495-501
In order to assess the influence of the steric crowding on the electro
chemical reduction of pyridycarboxamides, we have studied a series of
tertiary aromatic or alicyclic pyridylcarboxamides. We have shown that
increasing steric hindrance at the amide nitrogen led to the producti
on of either tetrahydropyridine or aminomethylpyridine.