During this study the absorption rates of two contrast media were meas
ured in double-blind design. 33 patients received lopamidol (Solutrast
300(R)), and 30 patients Meglumine lothalamate (Conray 60(R)). A regu
lar absorption of the contrast media during ERC, ERP and ERCP could be
stated. With reference to the absorption rates a slight, but for stat
istically not significant advantage for the contrast medium lopamidol
could be ascertained. During ERC the absorption rates ranged from 0.4
to 30%, during ERP from 2.2 to 18.8% and during ERCP from 1.0 and 30.0
%. Consequently the endoscopist always has to take into account an ana
phylactoid reaction due to the systemic absorption of contrast media w
hich, compared to other examinations with contrast media, happens rela
tively seldom.