In a cooperative, private practice, multi-institutional impotence stud
y, dynamic infusion cavernosometry and cavernosography (DICC) was perf
ormed on 743 patients to make an accurate diagnosis and/or identify ca
ndidates for penile revascularization. Maximum equilibrium intracorpor
eal pressure achieved following papaverine and phentolamine injection
(Phase I) averaged 29.42 +/- 0.76 mm Hg, approximately one third of no
rmal erection pressure. Corporeal pressure fall from 150 mm Hg over th
irty seconds (cavernosometry) averaged 82.38 +/- 1.33 mm Hg (Phase II)
. The gradient between systolic and cavernosal artery pressure average
d 42.84 +/- 1.12 mm Hg on the right and 43.33 +/- 1.13 mm Hg on the le
ft (Phase III). Cavernosography at 90 mm Hg erection pressure was perf
ormed in Phase IV. Of the 124 patients from one center who were review
ed in greater detail, pure cavernosal artery insufficiency (CAI) was f
ound in 25 (20.2%), corporeal veno-occlusive dysfunction (CVOD) in 26
(21.0%), and 73 patients (58.9%) demonstrated combined CAI and CVOD. D
iabetics (n = 69) achieved lower equilibrium intracorporeal pressures
than nondiabetics, had similar CVOD, and worse CAI. Smokers (n = 365)
and patients with Peyronie's disease (n = 32) had erectile dysfunction
similar to those without these conditions. Patients impotent after tr
auma (n = 124) were younger, achieved higher intracorporeal pressures,
and showed better corporeal veno-occlusive function than those withou
t trauma. Complications of DICC were minimal and infrequent. After DIC
C, 169 patients underwent internal pudendal arteriography, 105 had art
erial bypass surgery with or without penile venous ligation procedures
, and 45 had venous surgery alone. Dynamic infusion cavernosometry and
cavernosography is a useful erectile function study to evaluate impot
ence and can be performed easily in a private practice setting.