CONCENTRATION OF FREE CALCIUM IN ERYTHROCYTES OF LEAD-DEPLETED RATS

Authors
LOIPFUHRER AM REICHLMAYRLAIS AM KIRCHGESSNER M
Citation
Am. Loipfuhrer et al., CONCENTRATION OF FREE CALCIUM IN ERYTHROCYTES OF LEAD-DEPLETED RATS, Journal of trace elements and electrolytes in health and disease, 7(1), 1993, pp. 37-40
Citations number
24
Categorie Soggetti
Biology
Journal title
Journal of trace elements and electrolytes in health and disease → ACNP
ISSN journal
09312838
Volume
7
Issue
1
Year of publication
1993
Pages
37 - 40
Database
ISI
SICI code
0931-2838(1993)7:1<37:COFCIE>2.0.ZU;2-C
Abstract
The concentration of Ca2+-ions in erythrocytes of lead-depleted rats w as estimated using the fluorescent Ca2+-indicator fura-2. The lead-dep leted animals of the F1 generation showed an elevated Ca2+-concentrati on, whereas in the P(o) generation there was no difference in the Ca2-concentration between depletion and control group. The elevation of C a2+-ion concentration of lead-depleted rats could be caused by a reduc tion in Ca-Mg-ATPase activity in lead-depletion and could possibly lea d to a decreased mean corpuscular volume (MCV) of erythrocytes.