Laser-Doppler flowmetry (LDF) provides a reliable measurement of local
cerebral blood flow (lCBF) as demonstrated by multiple validation stu
dies. This article evaluates the clinical applications of LDF in neuro
surgery. With the availability of modified probes, it is possible to c
arry out LDF monitoring of neurosurgical patients in the intensive car
e unit. Currently, there are multiple systemic and intracranial parame
ters that are interactive and separately monitored. A multichanneled d
igital data acquisition system allows these data to be compiled in a s
ingle computer environment for the interpretation of lCBF changes. Gui
delines are suggested for the clinical use of LDF monitoring, and the
technical features of monitoring including the interpretation of data
are summarized.