Descriptive surveys of the epidemiology of inflammatory bowel disease
from the north and south of Europe show north-south gradient in its in
cidence and continue to point to lifestyle and environmental causes. T
his theme is further examined in studies of the causal association bet
ween inflammatory bowel disease and smoking, oral contraceptive use, a
nd diet by investigators from the United States and Europe, but the re
sults are not conclusive. Childhood exposure to environmental tobacco
smoke and the risk of ulcerative colitis is a new entry to the field t
hat shows decreased risk of ulcerative colitis in passive smokers.