LARGE-SCALE PRODUCTION OF INFECTIOUS BOVINE-RHINOTRACHEITIS VIRUS IN CELL-CULTURE ON MICROCARRIERS

Authors
LESKO J VEBER P HRDA M FEKETEOVA M
Citation
J. Lesko et al., LARGE-SCALE PRODUCTION OF INFECTIOUS BOVINE-RHINOTRACHEITIS VIRUS IN CELL-CULTURE ON MICROCARRIERS, Acta virologica, 37(1), 1993, pp. 73-78
Citations number
6
Categorie Soggetti
Virology
Journal title
Acta virologica → ACNP
ISSN journal
0001723X
Volume
37
Issue
1
Year of publication
1993
Pages
73 - 78
Database
ISI
SICI code
0001-723X(1993)37:1<73:LPOIBV>2.0.ZU;2-K
Abstract
Large amounts of infectious bovine rhinotracheitis (IBR) virus was pro duced in Madin-Darby bovine kidney (MDBK) cells in suspension culture on the microcarriers Gelaspher M. Virus yields (TCID50 per ml) were ap proximately 10-times higher as compared to clasical stationary cell cu lture.