It is now widely recognised that enteral feeds may become contaminated
with microorganisms during preparation and administration. Evidence i
s presented illustrasting the role of this contamination in the develo
pment of infectious complications, including bacteraemia, septicaemia,
pneumonia, diarrhoea and infectious entercolitis. Details are given o
f potential sources of microbial contamination including the feed ingr
edients, inadequately cleaned equipment, personnel and the patients th
emselves. Routes by which the microorganisms may gain access to the fe
eds, such as the procedures involved in the preparation and mixing of
ingredients, decanting of both mixed and sterile ready-to-use feeds an
d assembly and subsequent manipulation of the feeding systems, are con
sidered. Factors affecting the rate of growth of microorganisms in fee
ds and feeding systems are discussed and suggestions are made as to th
e procedures that can be implemented to reduce the risk of contaminati
on.