Yv. Yuan et Dd. Kitts, MILK PRODUCT AND CONSTITUENT PROTEIN EFFECTS ON PLASMA AND HEPATIC LIPIDS AND SYSTOLIC BLOOD-PRESSURE OF NORMOTENSIVE RATS, Food research international, 26(3), 1993, pp. 173-179
The effects of diets containing casein (C), whey protein concentrate (
W), skim milk protein concentrate (MPC), and yogurt powder (Y) on plas
ma total cholesterol, triacylglycerides and HDL-cholesterol (HDL-C), h
epatic total lipids and cholesterol levels were studied in normotensiv
e Wistar rats. Systolic blood pressure (SBP) was recorded weekly from
6 to 10 weeks of age. Diet effects were compared to animals fed soy pr
otein isolate (S) and, rat chow (RC) diets. Animals were meal fed unti
l 10 weeks of age, when blood and liver tissue samples were collected.
All groups exhibited similar growth rates. Animals fed C, W, MPC and
S diets exhibited similar plasma triacylglycerides and total cholester
ol levels, which were higher (p less-than-or-equal-to 0.05) than in Y
and RC animals. HDL-C was higher (p less-than-or-equal-to 0-05) in C,
W and MPC fed animals, than those fed Y or RC. HDL-C in S fed animals
only approached a significantly (p less-than-or-equal-to 0-07) lower a
mount compared to C, W and MPC fed animals. Hepatic total lipids and c
holesterol were not significantly (p > 0-05) different between groups.
The small changes in plasma lipids observed in animals fed dairy prod
ucts had little effect on SBP in normotensive rats.