CLINICAL POLYMORPHISM OF TUMOR AND VASCULAR DISEASES OF THE BRAIN - PATHOGENETIC ASPECTS

Using evidence on 533 patients with an atypical course of brain tumors and vascular diseases, the author discusses the role of the vascular factor in polymorphism of clinical manifestations of tumors and metast ases to the brain. It is shown that in 55.4% of cases brain tumors sim ulated CNS affections. Of these most frequent was the picture of cereb ral circulatory disturbances. Mechanisms causing cerebral circulation impairment in various tumors and metastases to the brain are considere d. It is found that pathologically changed circulation and angioarchit ecture of the tumors may contribute to a wide spectrum of clinical sig ns typical for vascular brain diseases. The conclusions are based on t he analysis of the results obtained with present-day techniques of ang io-and neurovisualization and postoperative as well as autopsy examina tions of the tumors.