MULTIPLE-SCLEROSIS - ACUTE FORMS OR A MALIGNANT COURSE

Multiple sclerosis (MS) which had developed in a 19-year-old female pa tient took a malignant course and terminated fatally three years after first symptoms. The case was characterized by an acute onset, seven s evere exacerbations against combined pyramidal, cerebellar, visual, ps ychopathological and hyperkinetic disorders. The authors believe impro per application of the term ''acute'' to rapid lethal outcome cases. i n their opinion, they should be called cases of MS malignant course, t he latter implying an unfavourable outcome of MS due to primarily trun cal location of the demyelination process.