Multivariate process control problems are inherently more difficult th
an univariate problems. It is not always clear what type of multivaria
te statistic should be used, and the most statistically powerful techn
iques do not indicate the cause(s) of a signal. On the other hand, sep
arate controls on the individual variables are more easily interpretab
le but may be substantially less powerful, particularly in the face of
appreciable correlation between the measures. Previous research has d
emonstrated the effectiveness of methods that capitalize on the likely
nature of a departure from control. If only one variable is likely to
undergo a shift in mean or variance then charting of each variable ad
justed by regression for all others is particularly effective. In this
paper, the issue of other possible regression adjustments is discusse
d. In particular, a regression of each variable for those driving it i
s considered. It is shown under what circumstances this adjustment is
appropriate, and its diagnostic power is illustrated by examples.