It was examined whether there is an association between physical healt
h and alterations of normal brain asymmetry in cerebral control of neu
roendocrine activity. In particular, it was studied whether right-hand
ed subjects showing a high amount of physical complaints and recurrent
diseases differ in direction and degree of brain asymmetry in cerebra
l control of cortisol secretion from subjects with only few physical c
omplaints. Lateralized brain activation was achieved by presenting an
emotionally aversive film to the subjects' left or right visual hemifi
eld, using a technique for lateralizing visual input that allows prolo
nged viewing while permitting free ocular scanning. Results revealed a
clear association between a high degree of physical complaints and al
tered brain asymmetry in cerebral control of neuroendocrine activity.