SQUALANE AS A POSSIBLE CARRIER OF BONE MORPHOGENETIC PROTEIN

Citation
T. Kawakami et al., SQUALANE AS A POSSIBLE CARRIER OF BONE MORPHOGENETIC PROTEIN, Biomaterials, 14(8), 1993, pp. 575-577
Citations number
8
Categorie Soggetti
Engineering, Biomedical","Material Science
Journal title
ISSN journal
01429612
Volume
14
Issue
8
Year of publication
1993
Pages
575 - 577
Database
ISI
SICI code
0142-9612(1993)14:8<575:SAAPCO>2.0.ZU;2-S
Abstract
Gelatin capsules containing squalane partially purified bone morphogen etic protein (BMP) complex were placed on the perimuscular membrane of rats. Two kinds of control, gelatin capsules containing only BMP and those bearing squalane only, were used. The embedded areas were histop athologically examined at 3 and 6 wk after the operation. The observat ions revealed that the squalane/BMP complex elicited wide heterotopic bone formation with bone marrow tissue, suggesting that squalane is a possible carrier of BMP for clinical applications.