A CONVENIENT SYNTHESIS OF CIS-4-(SULFOMETHYL)-PIPERIDINE-2-CARBOXYLICACID - NMR ASSIGNMENT

Authors
ELHADRI A LECLERC G
Citation
A. Elhadri et G. Leclerc, A CONVENIENT SYNTHESIS OF CIS-4-(SULFOMETHYL)-PIPERIDINE-2-CARBOXYLICACID - NMR ASSIGNMENT, Journal of heterocyclic chemistry, 30(3), 1993, pp. 631-635
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
30
Issue
3
Year of publication
1993
Pages
631 - 635
Database
ISI
SICI code
0022-152X(1993)30:3<631:ACSOC>2.0.ZU;2-5
Abstract
cis-4-(Sulfomethyl)piperidine-2-carboxylic acid was obtained in 22% ov erall yield from 4-(hydroxymethyl)-pyridine via the o-silyl N-oxide an d trimethylsilylcyanide. The cis configuration of 5 was unambiguously assigned by 200 MHz H-1 nmr and cosy experiments.