STRUCTURAL STUDY OF METHYL IPHENYL-N-METHYL-4-OXOPIPERIDINE-3,5-DICARBOXYLATE ENOLIC FORMS

Authors
FERNANDEZ MJ CASARES JM GALVEZ E BELLANATO J
Citation
Mj. Fernandez et al., STRUCTURAL STUDY OF METHYL IPHENYL-N-METHYL-4-OXOPIPERIDINE-3,5-DICARBOXYLATE ENOLIC FORMS, Journal of heterocyclic chemistry, 30(3), 1993, pp. 815-817
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
30
Issue
3
Year of publication
1993
Pages
815 - 817
Database
ISI
SICI code
0022-152X(1993)30:3<815:SSOMI>2.0.ZU;2-Q
Abstract
The methyl phenyl-1-methyl-4-oxopiperidine-3,5-dicarboxylates 1 were s ynthesized by the Mannich procedure from methyl 3-oxoglutarate, benzal dehyde and methylamine. Keto-enol tautomerism as well as configuration al isomerism at C-2 were observed. The stereochemistry of the Ib and I c enolic forms were determined by H-1 and C-13 nmr data.