J. Kupferschlager et al., A METHOD TO CORRECT MYOCARDIAL SPECT WITH TC-99M COMPOUNDS FOR SCATTER AND ATTENUATION WITHOUT TRANSMISSION, Nuklearmedizin, 36(2), 1997, pp. 56-64
Aim: A new strategy is introduced for a double-head gamma-camera to ca
lculate and to correct for attenuation distribution from countrates of
backscattered radiation of Tc-99m in the human thorax/myocardium set
ting. The intention was to gain segmented and calibrated images of dis
tribution employing the structures of lungs and other tissues; so that
attenuation may be subsequently corrected by the method of Chang. Met
hods: Acquisition was done simultanously in three energy windows for T
c-99m to receive both emitted and scattered radiation. The acquired pr
ojections were used to calculate the attenuation distribution and to e
xecute a scattercorrection by the method of Ogawa et. al. By measuring
phantoms and evaluating a set of patient studies, quality for both of
the approaches towards attenuated distribution and the quality of att
enuation correction was tested and an optimal setting for parameters i
nvolved was selected. Results: The procedure adequately approaches the
correction for both emitted and scattered radiation in SPECT, as expe
rienced in phantom and patient studies. Clinical usefulness was prelim
inary documented in selected cases. In normal perfusion, distribution
was more homogenous. Perfusion defects appeared more definitive Proble
ms occurred in high adjacent non-target activity (e.g., in the gallbla
dder) and with low countrate statistics. Conclusion: Myocardial Tc-99m
MIBI SPECT may be effectively corrected for both attenuation and scat
ter without an additional transmission device.