THE CHEMISTRY OF INDOLES .65. NUCLEOPHILIC-SUBSTITUTION REACTION OF 1-HYDROXYTRYPTOPHAN AND 1-HYDROXYTRYPTAMINE DERIVATIVES (REGIOSELECTIVESYNTHESES OF 5-SUBSTITUTED DERIVATIVES OF TRYPTOPHAN AND TRYPTAMINE)
M. Somei et Y. Fukui, THE CHEMISTRY OF INDOLES .65. NUCLEOPHILIC-SUBSTITUTION REACTION OF 1-HYDROXYTRYPTOPHAN AND 1-HYDROXYTRYPTAMINE DERIVATIVES (REGIOSELECTIVESYNTHESES OF 5-SUBSTITUTED DERIVATIVES OF TRYPTOPHAN AND TRYPTAMINE), Heterocycles, 36(8), 1993, pp. 1859-1866
Regioselective nucleophilic substitution at the 5-position of indole n
ucleus was observed in the reaction of 1-hydroxytryptophan and 1-hydro
xytryptamine derivatives with acids, suggesting the mechanism of serot
onin formation in the central nervous system.