SOLUBLE INTERLEUKIN-2 RECEPTOR AND INTERLEUKIN-2 IN HUMAN AMNIOTIC-FLUID OF NORMAL AND ABNORMAL PREGNANCIES

Authors
SHOHAT B SHOHAT M FAKTOR JH BARKAY G HARELL D KOZENITZKY L SHOHAT M
Citation
B. Shohat et al., SOLUBLE INTERLEUKIN-2 RECEPTOR AND INTERLEUKIN-2 IN HUMAN AMNIOTIC-FLUID OF NORMAL AND ABNORMAL PREGNANCIES, Biology of the neonate, 63(5), 1993, pp. 281-284
Citations number
10
Categorie Soggetti
Pediatrics
Journal title
Biology of the neonate → ACNP
ISSN journal
00063126
Volume
63
Issue
5
Year of publication
1993
Pages
281 - 284
Database
ISI
SICI code
0006-3126(1993)63:5<281:SIRAII>2.0.ZU;2-B
Abstract
In the present study, 63 specimens of human amniotic fluid were tested for the presence of free soluble interleukin-2 receptor (IL-2R). Thir ty-two of these were also tested for the presence of IL-2. Significant reduction in free soluble IL-2R (IU/ml) or free IL-2R (IU/mg albumin) levels were found in the amniotic fluid obtained from pregnant women with Down's syndrome fetuses as compared with normal pregnancies. In a ddition normal amniotic fluid was found to contain low levels of IL-2, while no IL-2 was found in amniotic fluid from pregnant women with Do wn's syndrome fetuses when tested by two different tests.