The electrochemical studies on vitamin B-12 and its derivatives were r
eviewed in this paper. The importance of electrochemical studies for e
xplaining the mechanism of B-12 coenzyme in body was discussed. The la
test results of electrochemical studies on vitamin B-12 and its deriva
tives was reviewed. A prospect for the electrochemical studies in vita
min B-12 and its derivatives was suggested.