STATISTICAL MIXTURE DESIGN APPLIED TO RP-HPTLC CHROMATOGRAPHIC SEPARATIONS OF AMINO-ACID HYDROXAMATES

Authors
WALTERS FH QIU HC
Citation
Fh. Walters et Hc. Qiu, STATISTICAL MIXTURE DESIGN APPLIED TO RP-HPTLC CHROMATOGRAPHIC SEPARATIONS OF AMINO-ACID HYDROXAMATES, Analytical letters, 26(8), 1993, pp. 1787-1797
Citations number
4
Categorie Soggetti
Chemistry Analytical
Journal title
Analytical letters → ACNP
ISSN journal
00032719
Volume
26
Issue
8
Year of publication
1993
Pages
1787 - 1797
Database
ISI
SICI code
0003-2719(1993)26:8<1787:SMDATR>2.0.ZU;2-5
Abstract
Mixture Design and a Chromatographic Response Function were used to st udy the effect of different organic solvents as modifiers on the Rever sed Phase (C-18) High Performance Thin Layer Chromatographic separatio n of three amino acid hydroxamates (Arginine hydroxamate, Threonine hy droxamate, and Histidine hydroxamate) . Both 3 solvent (methanol, acet onitrile and tetrahydrofuran) and 4 solvent (methanol, acetonitrite, t etrahydrofuran and acetone) systems were studied.