Ophthalmologic examinations were performed on the 176 eyes of 88 bedri
dden patients with severe dementia. There were some pathologic changes
in the external and anterior segments of 93 eyes. We observed infecti
ous external and anterior segment eye diseases in 80 of these 93 eyes
(86.0%). Fundus diseases were found in 34 eyes, but treatment was not
necessary. Infectious eye diseases appeared to be the most prevalent o
cular problem in these patients. Cultures of conjunctival swabs common
ly demonstrated Staphylococcus aureus. No differences were noted in te
ar secretion rate or lysozyme concentrations in tears between eyes wit
h and without infection. The blinking frequency was significantly redu
ced in infected eyes compared to normal eyes. Failure of the lacrimal
drainage system was observed more often in infected eyes than in norma
l eyes. This study demonstrated that bedridden patients with severe de
mentia develop infectious eye diseases easily, to which stasis of tear
flow seems to predispose. In caring for bedridden patients with sever
e dementia, ophthalmologists must be concerned with controlling infect
ious eye diseases.