THE MEASUREMENT OF FECAL THYROXINE IN THE DIAGNOSIS OF THYROTOXICOSIS-FACTITIA

Authors
BOUILLON R VERRESEN L STAELS F BEX M DEVOS P DEROO M
Citation
R. Bouillon et al., THE MEASUREMENT OF FECAL THYROXINE IN THE DIAGNOSIS OF THYROTOXICOSIS-FACTITIA, Thyroid, 3(2), 1993, pp. 101-103
Citations number
10
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Thyroid → ACNP
ISSN journal
10507256
Volume
3
Issue
2
Year of publication
1993
Pages
101 - 103
Database
ISI
SICI code
1050-7256(1993)3:2<101:TMOFTI>2.0.ZU;2-D
Abstract
Two patients with prolonged thyrotoxicosis are presented with low radi oiodide uptake, low-normal serum thyroglobulin concentrations, and low iodide content of the neck on x-ray fluorescence studies. The surrept itious intake of thyroid hormone was directly proven by a high fecal c oncentration of T4 (12.38 and 23.99 nmol/g) compared with low concentr ations in healthy subjects (1.03 +/- 0.64 nmol/g; mean +/- SD, n = 6) and in patients with hyperthyroidism due to Graves' disease (1.93 +/- 1.86; n = 8). Fecal thyroid hormone measurement may help to provide fo rmal proof of factitious thyrotoxicosis.