Different neural and thyroidal influences on mammalian skeletal muscle
result in considerable heterogeneity in muscle-fiber characteristics.
Muscle fibers can, nonetheless, be grouped into three relatively homo
geneous classes, based primarily on their contractile properties. Ther
e is a remarkable matching of metabolic support systems to contractile
properties and, in turn, appropriate vascular supply for the metaboli
c systems of each of the three muscle fiber types. The contractile, me
tabolic, and vascular characteristics of each fiber type are consisten
t with known patterns of muscle fiber recruitment for the performance
of muscular work.