MILD PHENOTYPIC MANIFESTATION OF A 7P15.3P21.2 DELETION

A 28 month old girl with dysmorphic features was found to have an inte rstitial deletion of the short arm of chromosome 7p15.3-7p21.2. The pa tient had ptosis, dacryostenosis, pectus excavatum, short hands, and h er development was normal or mildly delayed. Craniosynostosis and grow th retardation, which were present in two other patients with similar deletions, were not present. Because of the mild manifestations, this case expands the clinical spectrum of the 7p15-7p21 deletion phenotype .