AN IMPROVED SYNTHESIS OF 4-[3-(TRIFLUOROMETHYL)-3H-DIAZIRIN-3-YL]BENZOIC ACID FOR PHOTOAFFINITY-LABELING

Authors
HATANAKA Y NAKAYAMA H KANAOKA Y
Citation
Y. Hatanaka et al., AN IMPROVED SYNTHESIS OF 4-[3-(TRIFLUOROMETHYL)-3H-DIAZIRIN-3-YL]BENZOIC ACID FOR PHOTOAFFINITY-LABELING, Heterocycles, 35(2), 1993, pp. 997-1004
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
35
Issue
2
Year of publication
1993
Pages
997 - 1004
Database
ISI
SICI code
0385-5414(1993)35:2<997:AISO4>2.0.ZU;2-4
Abstract
An improved synthesis of 4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzo ic acid, a key carbene precursor for photoaffinity labeling, was descr ibed. A new diazirine with amino group as a connective part was design ed.