CYCLOADDITION REACTIONS WITH AZABENZENES .18. SYNTHESIS OF [2] PYRINDINES

Authors
NEUNHOEFFER H PHILIPP B SCHILDHAUER B ECKRICH R KRICHBAUM U
Citation
H. Neunhoeffer et al., CYCLOADDITION REACTIONS WITH AZABENZENES .18. SYNTHESIS OF [2] PYRINDINES, Heterocycles, 35(2), 1993, pp. 1089-1101
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
35
Issue
2
Year of publication
1993
Pages
1089 - 1101
Database
ISI
SICI code
0385-5414(1993)35:2<1089:CRWA.S>2.0.ZU;2-V
Abstract
The reaction of 1,2,4-triazines (1) and 1-cyclopentenylpyrrolidine (2) afforded 6,7-dihydro-5H-[2]-pyrindines (3) in good yields. Oxidation of 3 to the N-oxides (4), reaction of 4 with acetic anhydride to 5-ace toxy-6,7-dihydro-5H-[2]pyrindines (5) and elimination of acetic acid a fforded [2]pyrindines (7). 2-Methyl-2H-[2]pyrindines (9) were also pre pared.