A CONVENIENT SYNTHESIS OF PYRROLE-AMINOPYRROLE-3-PROPIONATE AND N-AMINOPYRROLE-3-PROPIONATE ESTERS

Authors
JACOBI PA CAI GL
Citation
Pa. Jacobi et Gl. Cai, A CONVENIENT SYNTHESIS OF PYRROLE-AMINOPYRROLE-3-PROPIONATE AND N-AMINOPYRROLE-3-PROPIONATE ESTERS, Heterocycles, 35(2), 1993, pp. 1103-1120
Citations number
39
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
35
Issue
2
Year of publication
1993
Pages
1103 - 1120
Database
ISI
SICI code
0385-5414(1993)35:2<1103:ACSOPA>2.0.ZU;2-N
Abstract
Trisubstituted pyrroles having a substitution pattern found in many na turally occurring linear and macrocyclic tetrapyrroles have been prepa red in a regiospecific fashion by a two step sequence involving Diels- Alder reaction of 2-oxo-3-butenoate esters (Sg) with 2-alkoxy-1,3-pent adiene derivatives (46), followed by ozonolysis and Paal-Knorr cycliza tion.