Pulse-synchronous tinnitus (PT) is deemed rare, but may be the first s
ymptom of a variety of causes. Between 1987 and 1990, we have studied
23 patients with objective (n = 14) or subjective (n = 9) PT. In 10 pa
tients, PT was the sole complaint. Final diagnoses included dural (n =
9) or pial (n = 1) arteriovenous malformation, carotid-cavernous fist
ula (n = 3), glomus tumor (n = 3), intracranial carotid stenosis (n =
2), complicated migraine (n = 1), subarachnoid hemorrhage associated w
ith Marfan's syndrome (n = 1), benign intracranial hypertension (n = 1
), and venous PT of unknown cause (n = 1). Doppler ultrasound revealed
pertinent pathologic findings in 11 of 13 patients studied. Angiograp
hy established the final diagnosis in 18 of 21 patients. Therapy reduc
ed or abolished PT in 16 patients. Our findings indicate that unusual
causes must be considered in the diagnosis of PT. Even in isolated or
subjective PT, a staged diagnostic work-up including angiography shoul
d be initated.