DERMATOFIBROSARCOMA PROTUBERANS APPEARING DURING PREGNANCY

Dermatofibrosarcoma protuberans is an uncommon skin tumor with a high potential for local recurrence if not adequately excised. There are on ly two reports in the literature describing dermatofibrosarcoma protub erans that enlarged considerably during pregnancy. On the other hand, the new development or enlargement of dermatofibromas in pregnancy is well documented. We present 2 additional patients in whom a dermatofib rosarcoma protuberans appeared and grew rapidly during pregnancy. Immu nohistochemical studies were negative for estrogen and progesterone re ceptors. The possible pathophysiology and surgical management are pres ented and discussed.