L)-3,7,8-TRIALKYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONES

Authors
RYBAR A TURCANI P ALFOLDI J
Citation
A. Rybar et al., L)-3,7,8-TRIALKYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONES, Collection of Czechoslovak Chemical Communications, 58(5), 1993, pp. 1169-1179
Citations number
7
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
58
Issue
5
Year of publication
1993
Pages
1169 - 1179
Database
ISI
SICI code
0010-0765(1993)58:5<1169:L>2.0.ZU;2-6
Abstract
1-(2-Oxopropyl)-, 1-(3-oxobutyl)-, and l)-3,7,8-trialkyl-3,7-dihydro-1 H-purine-2.6-diones (Ia - Xa, Ib - Xb, and Ic - Xc, respectively) were prepared by alkylation of alkali metal salts of 3,7,8-trialkyl-3,7-di hydro-1H-purine-2.6-diones XI - XX with chloroacetone or 6-chloro-2-he xanone or by addition of the starting diones XI - XX to methyl vinyl k etone. The effect of the final compounds I - X on aggregation of throm bocytes and erythrocytes was investigated.