Thermography is an investigative technique which allows rapid color-co
ded display of the temperature across a wide surface by means of infra
red detection. We describe an ocular thermographic study of a normal p
opulation and present case studies describing the application of this
technique for patients with ocular disease. We found that 95% of the n
ormal population have an interocular temperature difference (temperatu
re of center of right cornea minus temperature of center of left corne
a) of 0.60-degrees-C or less. There appears to be a greater difference
in temperature between the limbus and the center of the cornea in pat
ients with dry eyes. This technique has potential for evaluating tear
film disorders and inflammatory conditions, for monitoring the progres
s of such conditions, and for evaluating the efficacy of various treat
ments.