If the sigmoid and transverse sinuses could be divided safely, surgeon
s could broaden their access during skull base surgery without retract
ing the brain extensively. We undertook this study in monkeys to asses
s the risk of sacrificing these sinuses. We learned that when bilatera
l transverse sinuses were occluded, the sinus pressure measured in the
superior sagittal sinus increased significantly as blood was purged f
rom sinus venules. Unilateral sacrifice of sigmoid and transverse sinu
ses, however, did not change proximal sinus pressure in any ipsilatera
l or contralateral sinus. Furthermore, no change in regional cerebral
blood flow or motor evoked potentials was seen in the parietal lobe no
r did auditory brainstem response change significantly with sinus abla
tion. We conclude that, unilaterally, sigmoid and transverse sinuses m
ay be ablated safely because collateral circulation via the vein of La
bbe, superior petrosal sinus, petrosal vein, and backflow from the tra
nsverse sinus to the contralateral sinus may be established.