MUCIN-PRODUCING POORLY DIFFERENTIATED ADENOCARCINOMA OF THE THYROID -A CASE-REPORT

A rare case of mucin-producing poorly differentiated adenocarcinoma of the thyroid is reported in a 58-year-old man. Light microscopically, the tumor composed of columnar cells, cuboidal cells and spindle cells and these tumor cells showed a various growth pattern; glandular grow th with columnar cells, microfollicular growth with cuboidal cells and solid growth with spindle cells. Mucin histochemistry showed scattere d foci of mucin production. Immunohistochemistry showed a focal positi ve staining for thyroglobulin and carcinoembryonic antigen, but a nega tive staining for calcitonin throughout the tumor. The patient had cer vical and axillar lymph node recurrences after the radical operation. The histologic finding of this tumor is peculiar; we report this case briefly.