A. Tadayyon et al., CONTACT-SORPTION DRYING OF PENICILLIUM-BILAII IN A FLUIDIZED-BED DRYER, Journal of chemical technology and biotechnology, 68(3), 1997, pp. 277-282
A fluidized bed dryer and drying system have been designed, constructe
d and operated to produce a powdered formulation of the fungus Penicil
lium bilaii. The dryer includes an air-shear atomizer and rotatable ai
r vibrator to produce particles which are evenly coated with P. bilaii
. The drying system included a humidifier, oven, vacuum pump and instr
umentation to ensure precise control of operating conditions. Instant
skim milk powder was found to be the best particle source for fixing t
he spores due to its solubility in water, its highly porous nature and
because its moisture isotherms were similar to those of the spores. T
he dryer was operated at 35 degrees C to maximize the drying rate whil
e still preventing thermal death of the spores. The fluidizing air was
best provided at an RH of 30%, thereby producing skim milk/spore part
icles with just the right amount of moisture to ensure long term stora
ge viability. Storage under refrigeration conditions showed little lon
g term decline in spore viability after 3 months of tests. Room temper
ature storage demonstrated a small decline rate in spore viability wit
h little significant change if held at room temperature for a few days
.