Extraskeletal osseous and cartilaginous tumors and tumorlike condition
s of the extremities can often be differentiated radiologically; for t
hose that cannot, knowledge of the spectrum of lesions will allow a su
itably ordered differential diagnosis. Of the osseous lesions-myositis
ossificans, fibro-osseous pseudotumor, fibrodysplasia ossificans prog
ressiva soft-tissue osteoma, and extraskeletal osteosarcoma-all but my
ositis ossificans are relatively rare. Myositis ossificans has a disti
nct mineralization pattern that can be observed radiologically as a pe
ripheral rim of lamellar bone. Fibro-osseous pseudotumor typically occ
urs in the digits of the hand and lacks the well-defined zoning patter
n of myositis ossificans. The cartilaginous entities include the true
tumors, soft-tissue chondroma and extraskeletal chondrosarcoma, and th
e tumorlike process, synovial osteochondromatosis. The tumors are rela
tively rare; synovial osteochondromatosis commonly affects middle-aged
men, especially in the knee, and is associated with osteoarthritis. T
he differential diagnosis for these extraskeletal osseous and cartilag
inous lesions includes soft-tissue sarcoma, benign mesenchymoma, malig
nant mesenchymoma (rare), calcified tophi in gout. melorheostosis (rar
e), pilomatricoma (rare), and tumoral calcinosis (rare).