MOBILE ELEMENTS DISTRIBUTION AND QUANTITA TIVE CHARACTER PENETRANCE IN THE SCUTE MUTANTS OF DROSOPHILA-MELANOGASTER INDUCED IN THE SYSTEM OF P-M HYBRID DYSGENESIS
Dp. Furman et al., MOBILE ELEMENTS DISTRIBUTION AND QUANTITA TIVE CHARACTER PENETRANCE IN THE SCUTE MUTANTS OF DROSOPHILA-MELANOGASTER INDUCED IN THE SYSTEM OF P-M HYBRID DYSGENESIS, Genetika, 29(6), 1993, pp. 960-977
A series of new scute mutants noted for reduction in one pair of brist
les (humerals), but different penetrance with respect to this characte
r, were unduced in the system of P-M hybrid dysgenesis. In situ hybrid
ization technique was used to determine the sites of the MEs pertainin
g to six families in 6 scute mutants and 18 isogenic lined derived fro
m those. Through calculating the similarity indeces, similarity with r
espect to the pattern of total distribution of all MEs examined was es
timated for the lines. Results obtained favour the correlation between
penetrance and ME localization. The <<ME pattern-penetrance>> depende
nce was verified using the isogenic lines. The matrix of similarity in
deces and the similarity tree were constructed for the mutant lines fo
llowing comparative analysis of distribution of 132 hybridization site
s. The structure of the tree gies in a number (3-4) of blocks made up
by isogenic lines of different origin. The rank of stocks following me
rely ordering them as regards penetrance and the structure of both the
tree and the matrix run together pretty well; what's, more, compact b
locks of labelled sites answer to the groups of stocks of close penetr
ance. Our results suggest that penetrance with respect to the number o
f numerals should directly depend on the peculiarites of ME localizati
on in the genomes of mutant lines.