The origin of genes in Talysh population (South Azerbaijan Republic) i
s considered. During 11 generations of population history more than 10
0 unrelated persons supplied the genes to the population. At present,
the population is highly isolated: the endogamy index is 0,878, gameti
c index being 0,935. Inbreeding is estimated both ty means of genealog
y and from the frequency of marriages between the persons of the same
kin. The inbreeding coefficient is F(IT)=0,026-0,030, its random compo
nent is F(ST)=0,01-0,02 and non-random component is F(IS)=0,026-0,020.