RED-BLOOD-CELL MEMBRANE LIPID-COMPOSITION IN IRON-DEFICIENCY ANEMIA PATIENTS DURING TREATMENT

Citation
Np. Kirilenko et Iv. Paramonova, RED-BLOOD-CELL MEMBRANE LIPID-COMPOSITION IN IRON-DEFICIENCY ANEMIA PATIENTS DURING TREATMENT, Gematologia i transfuziologia, 37(11-12), 1992, pp. 20-23
Citations number
NO
Categorie Soggetti
Hematology
ISSN journal
02345730
Volume
37
Issue
11-12
Year of publication
1992
Pages
20 - 23
Database
ISI
SICI code
0234-5730(1992)37:11-12<20:RMLIIA>2.0.ZU;2-K
Abstract
Red blood cell membrane lipid composition was studied in 51 iron defic iency anemia patients, in 10 of them during ferrotherapy. It was noted that red blood cell membranes contained increased total levels of lip ids, phospholipids and significantly decreased levels of cholesterol e sters and lysophospholipids. During the treatment, in the presence of a distinct process of the recovery of disturbed lipid composition of r ed blood cell membranes, a significant increase was recorded in the co ntent of triglycerides, phosphatidyl amines, while phosphatidyl and ca rdiolipin levels were significantly lowered. Red blood cell membrane l ipid content in iron deficiency anemia patients and its dynamics in th e process of their treatment might serve, as an additional criteria of the body saturation with iron.