Np. Kirilenko et Iv. Paramonova, RED-BLOOD-CELL MEMBRANE LIPID-COMPOSITION IN IRON-DEFICIENCY ANEMIA PATIENTS DURING TREATMENT, Gematologia i transfuziologia, 37(11-12), 1992, pp. 20-23
Red blood cell membrane lipid composition was studied in 51 iron defic
iency anemia patients, in 10 of them during ferrotherapy. It was noted
that red blood cell membranes contained increased total levels of lip
ids, phospholipids and significantly decreased levels of cholesterol e
sters and lysophospholipids. During the treatment, in the presence of
a distinct process of the recovery of disturbed lipid composition of r
ed blood cell membranes, a significant increase was recorded in the co
ntent of triglycerides, phosphatidyl amines, while phosphatidyl and ca
rdiolipin levels were significantly lowered. Red blood cell membrane l
ipid content in iron deficiency anemia patients and its dynamics in th
e process of their treatment might serve, as an additional criteria of
the body saturation with iron.