The role of feedback connections from area V2 to V1 was studied by rev
ersible inactivation. When V2 was inactivated, the responses of some V
1 neurons to stimulation of the surround region were increased while r
esponses to center stimulation were unchanged or decreased. Latencies
to small flashing stimuli were also compared in areas V1 and V2. The d
istributions in the two areas overlap largely, with a 10 ms shift betw
een the two. Neurons of V1 and V2 that are driven by the magnocellular
layers of the LGN are activated 20 ms earlier than neurons of the par
vocellular stream.