This is a retrospective review of the presentation, diagnosis, treatme
nt, and outcome of 19 patients who injured the tarsometatarsal joint o
f the foot during athletic activity. Diagnosis by clinical and radiogr
aphic examination was supplemented by stress fluoroscopy of the articu
lation under anesthesia. Injuries were classified as either a first- o
r second-degree sprain of the tarsometatarsal joint, a third-degree sp
rain (with diastasis between the metatarsals or cuneiforms), a fractur
e, or frank dislocation. Poor functional results were seen in those fo
r whom diagnosis was delayed and for whom the injury was not treated a
dequately. Three patients were unable to return to sports, one of whom
eventually required fusion of the tarsometatarsal joint. The third-de
gree sprains were indistinguishable from fracture and fracture-disloca
tions in that good results were not reliably obtained by nonoperative
treatment, and both classes of injury seem to require open reduction a
nd internal fixation for optimal return to function. The delay in retu
rn to full activity is a marker of the severity of this injury despite
an often benign appearance on radiograph.