Peritonitis was diagnosed in 67 horses between 1985 and 1990: 14 horse
s developed septic peritonitis after intestinal rupture, 25 horses dev
eloped peritonitis after abdominal surgery, and 28 horses had peritoni
tis not associated with intestinal rupture or abdominal surgery. Forty
of 67 horses (59.7%) did not survive. Nonsurvivors had higher heart r
ates (P = 0.01), RBC count (P = 0.039), serum creatinine concentration
(P = 0.036), PCV (P = 0.007), and anion gap (P = 0.005); lower venous
blood pH (P = 0.002); and a greater number of bacterial species cultu
red from peritoneal fluid samples (P = 0.054), compared with those fro
m survivors. Nonsurvivors were more likely to have signs of abdominal
pain (P < 0.000), circulatory shock (P = 0.009), and bacteria in perit
oneal fluid samples (P = 0.042). Physical examination and peritoneal f
luid analysis were the most valuable diagnostic aids for intestinal ru
pture. Peritonitis after abdominal surgery resulted in high mortality
(56%); peritonitis not associated with intestinal rupture or abdominal
surgery had lower mortality (42.9%). Clinical and laboratory indices
can be of value in determining the prognosis for horses with peritonit
is.