V. Moll et al., KIDNEY PRESERVING SURGERY IN RENAL-CELL TUMORS - INDICATIONS, TECHNIQUES AND RESULTS IN 152 PATIENTS, The Journal of urology, 150(2), 1993, pp. 319-323
Between 1975 and 1991, 142 patients with renal cell carcinoma and 10 w
ith oncocytoma underwent a total of 164 kidney preserving operations.
The indication for surgery was imperative (group 1, 47 patients) among
those with a solitary kidney (9), renal insufficiency (17) or bilater
al tumors (21). Of the patients with small or peripheral tumors and a
healthy contralateral kidney 105 were selected for elective surgery (g
roup 2). Most procedures were done either without ischemia (24%) or wi
th warm ischemia (69%). In some patients from the imperative indicatio
n group hypothermia was achieved by in situ perfusion (5%) or ex vivo
work bench surgery and autotransplantation (2%). Complication rates we
re 15% for group 1 and 9.5% for group 2. In group 1, 3 patients died o
f cancer, 5 lived with metastases and 2 had local tumor recurrence. No
patient in group 2 had recurrences or metastases. The tumor-specific
survival rate of patients with kidney preservation for renal cell carc
inoma was comparable to that of a control group undergoing radical nep
hrectomy. Due to the high reliability and efficacy, kidney preserving
surgery for renal cell carcinoma should be done more often, even in pa
tients with a normally functioning contralateral kidney.