CHRONIC BIOFILTRATION THERAPY

Long-term follow-up evaluation of biofiltration treatment in 7 patient s is presented. These patients experienced frequent episodes of hypote nsion during acetate hemodialysis. A 3-year biofiltration treatment re duced by 43% episodes of symptomatic hypotension and produced a signif icant increase in the pretreatment pH and plasma bicarbonate levels. T he beta2-Microglobulin level was significantly reduced during biofiltr ation therapy. The mean systolic and diastolic blood pressures slightl y increased during biofiltration. Uremic polyneuropathy, as demonstrat ed by an increase in motor nerve conduction velocity, slightly improve d. The patients reported increased comfort during biofiltration therap y.