IONIZING-RADIATION INDUCED EFFECTS ON CEPHRADINE - INFLUENCE OF SAMPLE MOISTURE-CONTENT, IRRADIATION DOSE AND STORAGE-CONDITIONS

Authors
SIGNORETTI EC ONORI S VALVO L FATTIBENE P SAVELLA AL DESENA C ALIMONTI S
Citation
Ec. Signoretti et al., IONIZING-RADIATION INDUCED EFFECTS ON CEPHRADINE - INFLUENCE OF SAMPLE MOISTURE-CONTENT, IRRADIATION DOSE AND STORAGE-CONDITIONS, Drug development and industrial pharmacy, 19(14), 1993, pp. 1693-1708
Citations number
13
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Drug development and industrial pharmacy → ACNP
ISSN journal
03639045
Volume
19
Issue
14
Year of publication
1993
Pages
1693 - 1708
Database
ISI
SICI code
0363-9045(1993)19:14<1693:IIEOC->2.0.ZU;2-E
Abstract
The effects of gamma and electron beam irradiation. on cephradine were studied as a function of dose. In particular, degradation products an d free radicals induced by radiation on samples with different moistur e content were investigated. The influence of daylight on the kinetics of the degradation processes was also evaluated.